STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYMSThymidylate synthetase. (173 aa)    
Predicted Functional Partners:
tk1
Thymidine kinase.
  
 
 0.975
dhfr
Dihydrofolate reductase.
 
 
 0.973
LOC107082490
Zgc:153031.
 
 
 0.964
itpa
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
  
 
 0.951
gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.944
fpgs
Folylpolyglutamate synthase.
     
 0.943
rnaseh1
Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
 0.936
spata20
Spermatogenesis associated 20.
    
  0.892
iba57
Iron-sulfur cluster assembly factor IBA57.
    
  0.881
dtymk
Deoxythymidylate kinase (thymidylate kinase).
  
 
 0.860
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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