STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gphnMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (775 aa)    
Predicted Functional Partners:
mocs2
Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.
 
 
 0.994
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
  
 
 0.944
mocs1
Molybdenum cofactor synthesis 1.
 
 0.843
irak1
Interleukin-1 receptor-associated kinase 1.
    
 
 0.730
Suox
Sulfite oxidase.
   
 
 0.724
GLRB
Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 
 0.704
LOC107099597
Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 
 0.704
tmem187
Transmembrane protein 187.
      
 0.671
LOC107082507
Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
      
 0.668
gnl3l
Guanine nucleotide binding protein-like 3 (nucleolar)-like.
     
 0.665
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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