STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARAndrogen receptor. (384 aa)    
Predicted Functional Partners:
LOC107090031
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
     
 0.914
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.907
LOC107093417
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
     
 0.907
prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.907
ar
Nuclear receptor domain-containing protein.
     
 
0.900
mdm2
MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.
    
 
 0.844
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.807
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 
 0.807
LOC107101922
Peptidylprolyl isomerase.
    
 0.790
ENSCVAP00000002779
GPS2_interact domain-containing protein.
    
 0.730
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.