STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107091747Neurofibromin 2b (merlin). (591 aa)    
Predicted Functional Partners:
LOC107089879
Angiomotin.
    
 0.968
LOC107083391
Angiomotin like 2b.
    
 0.943
amotl2
Angiomotin like 2a.
    
 0.943
nf2
Neurofibromin 2a (merlin).
  
  
 
0.901
lats1
Large tumor suppressor kinase 1.
    
 
 0.756
lats2
Large tumor suppressor kinase 2.
    
 
 0.724
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 
 0.719
ENSCVAP00000030672
Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
    
 
 0.672
PAK3
Non-specific serine/threonine protein kinase.
   
 0.611
pak1
Non-specific serine/threonine protein kinase.
   
 0.611
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.