STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spire2Spire-type actin nucleation factor 2. (771 aa)    
Predicted Functional Partners:
LOC107082021
GRB2 related adaptor protein 2a.
   
 0.741
plekhj1
Pleckstrin homology domain containing, family J member 1.
    
 
 0.673
fancf
FA complementation group F.
      
 0.664
prepl
Prolyl endopeptidase like.
      
 0.664
sf3a2
Splicing factor 3a, subunit 2.
      
 0.664
grb2
Growth factor receptor-bound protein 2b.
   
 0.632
LOC107101690
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.542
gabra5
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.542
gas2
Growth arrest-specific 2a.
   
 0.537
nck2
Cytoplasmic protein.
    
 0.523
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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