rest protein (Cyprinodon variegatus) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

rest

RE1-silencing transcription factor. (999 aa)

Predicted Functional Partners:

kdm1a

0.880

rcor1

0.878

rcor3

0.796

rcor2

0.796

phf21a

0.687

arid4b

0.647

rbbp4

0.643

sin3a

0.642

LOC107095362

0.642

sin3b

0.642

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107095362	arid4b	ENSCVAP00000016383	ENSCVAP00000002162	SIN3 transcription regulator family member Ab.	Translocase of outer mitochondrial membrane 20.	0.928
LOC107095362	rbbp4	ENSCVAP00000016383	ENSCVAP00000026884	SIN3 transcription regulator family member Ab.	Retinoblastoma binding protein 4.	0.872
LOC107095362	rest	ENSCVAP00000016383	ENSCVAP00000003703	SIN3 transcription regulator family member Ab.	RE1-silencing transcription factor.	0.642
arid4b	LOC107095362	ENSCVAP00000002162	ENSCVAP00000016383	Translocase of outer mitochondrial membrane 20.	SIN3 transcription regulator family member Ab.	0.928
arid4b	kdm1a	ENSCVAP00000002162	ENSCVAP00000028102	Translocase of outer mitochondrial membrane 20.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.656
arid4b	phf21a	ENSCVAP00000002162	ENSCVAP00000013914	Translocase of outer mitochondrial membrane 20.	PHD finger protein 21Ab.	0.744
arid4b	rbbp4	ENSCVAP00000002162	ENSCVAP00000026884	Translocase of outer mitochondrial membrane 20.	Retinoblastoma binding protein 4.	0.994
arid4b	rcor1	ENSCVAP00000002162	ENSCVAP00000008418	Translocase of outer mitochondrial membrane 20.	REST corepressor 1.	0.664
arid4b	rcor2	ENSCVAP00000002162	ENSCVAP00000024343	Translocase of outer mitochondrial membrane 20.	REST corepressor 2.	0.664
arid4b	rcor3	ENSCVAP00000002162	ENSCVAP00000015577	Translocase of outer mitochondrial membrane 20.	REST corepressor 3.	0.664
arid4b	rest	ENSCVAP00000002162	ENSCVAP00000003703	Translocase of outer mitochondrial membrane 20.	RE1-silencing transcription factor.	0.647
arid4b	sin3a	ENSCVAP00000002162	ENSCVAP00000008738	Translocase of outer mitochondrial membrane 20.	SIN3 transcription regulator family member Aa.	0.928
arid4b	sin3b	ENSCVAP00000002162	ENSCVAP00000018936	Translocase of outer mitochondrial membrane 20.	SIN3 transcription regulator family member B.	0.928
kdm1a	arid4b	ENSCVAP00000028102	ENSCVAP00000002162	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Translocase of outer mitochondrial membrane 20.	0.656
kdm1a	phf21a	ENSCVAP00000028102	ENSCVAP00000013914	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	PHD finger protein 21Ab.	0.961
kdm1a	rbbp4	ENSCVAP00000028102	ENSCVAP00000026884	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Retinoblastoma binding protein 4.	0.919
kdm1a	rcor1	ENSCVAP00000028102	ENSCVAP00000008418	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	REST corepressor 1.	0.969
kdm1a	rcor2	ENSCVAP00000028102	ENSCVAP00000024343	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	REST corepressor 2.	0.945
kdm1a	rcor3	ENSCVAP00000028102	ENSCVAP00000015577	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	REST corepressor 3.	0.945
kdm1a	rest	ENSCVAP00000028102	ENSCVAP00000003703	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	RE1-silencing transcription factor.	0.880