STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spry4Sprouty homolog 4 (Drosophila). (381 aa)    
Predicted Functional Partners:
LOC107098202
Uncharacterized protein.
    
 0.769
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.769
LOC107083535
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.769
grb2
Growth factor receptor-bound protein 2b.
    
 0.635
spry1
Sprouty homolog 1, antagonist of FGF signaling (Drosophila).
   
0.603
LOC107088092
GRB2 related adaptor protein a.
    
 0.588
LOC107086417
GRB2 related adaptor protein b.
    
 0.588
LOC107082021
GRB2 related adaptor protein 2a.
    
 0.588
LOC107104990
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.541
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.541
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.