STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aplp1Amyloid beta (A4) precursor-like protein 1. (707 aa)    
Predicted Functional Partners:
ENSCVAP00000016004
Uncharacterized protein.
    
 0.751
ENSCVAP00000010755
Uncharacterized protein.
    
 0.722
Nfkbid
ANK_REP_REGION domain-containing protein.
    
 0.693
Sdhaf1
Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family.
      
 0.672
prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.665
HLCS
Holocarboxylase synthetase.
      
 0.664
NCSTN
Nicastrin.
    
 0.658
tnfrsf21
Tumor necrosis factor receptor superfamily, member 21.
    
 
 0.603
fkrp
Fukutin related protein.
      
 0.596
LOC107099431
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.566
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.