Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)    
Predicted Functional Partners:
LOC107101186
Mitogen-activated protein kinase.
   
0.984
mapk1
Mitogen-activated protein kinase.
   
0.984
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.984
LOC107104990
A-Raf proto-oncogene, serine/threonine kinase.
   
0.982
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
0.982
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.982
map3k8
Mitogen-activated protein kinase kinase kinase 8.
  
0.977
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.940
pak2
Non-specific serine/threonine protein kinase.
  
 
0.939
PAK3
Non-specific serine/threonine protein kinase.
  
 
0.938
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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