STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCVAP00000004758A2M_N_2 domain-containing protein. (1027 aa)    
Predicted Functional Partners:
c9
Complement component 9.
   
 0.981
C8A
Complement C8 alpha chain.
   
 0.968
LOC107092244
Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family.
   
 0.950
cfi
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.837
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.826
C5AR1
Complement C5a receptor 1.
    
 0.820
LOC107098502
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.705
LOC107098503
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.705
LOC107102499
Si:ch1073-280e3.1; Belongs to the peptidase S1 family.
   
 0.689
LOC107084203
Vitronectin b.
   
 0.683
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.