ENSCVAP00000004841 protein (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSCVAP00000004841

Uncharacterized protein. (92 aa)

Predicted Functional Partners:

wdr61

0.876

ccdc97

0.870

phf5a

0.866

get3

0.815

sec61b

0.803

get4

0.774

zrsr2

0.773

sf3b6

0.764

leo1

0.705

CLPB

0.640

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPB	ENSCVAP00000004841	ENSCVAP00000014804	ENSCVAP00000004841	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.640
CLPB	get3	ENSCVAP00000014804	ENSCVAP00000026115	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.515
CLPB	get4	ENSCVAP00000014804	ENSCVAP00000001177	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Guided entry of tail-anchored proteins factor 4.	0.425
ENSCVAP00000004841	CLPB	ENSCVAP00000004841	ENSCVAP00000014804	Uncharacterized protein.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.640
ENSCVAP00000004841	ccdc97	ENSCVAP00000004841	ENSCVAP00000021270	Uncharacterized protein.	Coiled-coil domain containing 97.	0.870
ENSCVAP00000004841	get3	ENSCVAP00000004841	ENSCVAP00000026115	Uncharacterized protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.815
ENSCVAP00000004841	get4	ENSCVAP00000004841	ENSCVAP00000001177	Uncharacterized protein.	Guided entry of tail-anchored proteins factor 4.	0.774
ENSCVAP00000004841	leo1	ENSCVAP00000004841	ENSCVAP00000026133	Uncharacterized protein.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.705
ENSCVAP00000004841	phf5a	ENSCVAP00000004841	ENSCVAP00000023033	Uncharacterized protein.	PHD finger protein 5A.	0.866
ENSCVAP00000004841	sec61b	ENSCVAP00000004841	ENSCVAP00000007694	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.803
ENSCVAP00000004841	sf3b6	ENSCVAP00000004841	ENSCVAP00000022367	Uncharacterized protein.	Splicing factor 3b, subunit 6.	0.764
ENSCVAP00000004841	wdr61	ENSCVAP00000004841	ENSCVAP00000008802	Uncharacterized protein.	WD repeat domain 61.	0.876
ENSCVAP00000004841	zrsr2	ENSCVAP00000004841	ENSCVAP00000017754	Uncharacterized protein.	Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2.	0.773
ccdc97	ENSCVAP00000004841	ENSCVAP00000021270	ENSCVAP00000004841	Coiled-coil domain containing 97.	Uncharacterized protein.	0.870
ccdc97	phf5a	ENSCVAP00000021270	ENSCVAP00000023033	Coiled-coil domain containing 97.	PHD finger protein 5A.	0.848
ccdc97	sf3b6	ENSCVAP00000021270	ENSCVAP00000022367	Coiled-coil domain containing 97.	Splicing factor 3b, subunit 6.	0.973
ccdc97	zrsr2	ENSCVAP00000021270	ENSCVAP00000017754	Coiled-coil domain containing 97.	Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2.	0.931
get3	CLPB	ENSCVAP00000026115	ENSCVAP00000014804	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.515
get3	ENSCVAP00000004841	ENSCVAP00000026115	ENSCVAP00000004841	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Uncharacterized protein.	0.815
get3	get4	ENSCVAP00000026115	ENSCVAP00000001177	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Guided entry of tail-anchored proteins factor 4.	0.996