STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sos2Son of sevenless homolog 2 (Drosophila). (1325 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.997
LOC107098892
Receptor protein-tyrosine kinase.
    
 0.967
egfr
Receptor protein-tyrosine kinase.
    
 0.967
hras
HRas proto-oncogene, GTPase a.
   
 0.966
LOC107095138
Zgc:55558.
   
 0.965
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.965
LOC107081801
Fibroblast growth factor receptor.
    
 0.949
mras
Muscle RAS oncogene homolog.
   
 0.945
fgfr2
Fibroblast growth factor receptor 2.
    
 0.944
LOC107087110
Fibroblast growth factor receptor.
    
 0.941
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.