STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCVAP00000004949CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (119 aa)    
Predicted Functional Partners:
gtf2f1
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.782
timm23
Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
    
 0.692
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
 0.686
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
    
 0.660
timm21
Uncharacterized protein.
    
 0.651
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J.
   
 0.614
supt5h
Transcription elongation factor SPT5.
    
 0.596
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
   
 0.588
LOC107083529
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
   
 0.583
cnep1r1
CTD nuclear envelope phosphatase 1 regulatory subunit 1.
   
 0.583
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.