STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCVAP00000005575G2/M-phase specific E3 ubiquitin protein ligase. (648 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.723
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.717
ankrd46
Ankyrin repeat domain 46b.
    
 0.583
eed
Embryonic ectoderm development.
   
 0.582
ENSCVAP00000005944
PP1-binding domain-containing protein.
   
  
 0.550
LOC107093481
SUZ12 polycomb repressive complex 2 subunit b.
   
 0.521
LOC107087701
VEFS-Box domain-containing protein.
   
 0.521
cdca8
Cell division cycle associated 8.
   
 0.517
mphosph8
Chromo domain-containing protein.
    
 0.501
ncapd2
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
      
 0.491
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.