mkrn1 protein (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mkrn1

Makorin, ring finger protein, 1. (431 aa)

Predicted Functional Partners:

trip12

0.758

ENSCVAP00000021667

0.619

rps27a

0.541

fech

0.497

PTEN

0.452

LOC107094800

0.452

LOC107087905

0.452

uba5

0.402

atg7

0.402

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000021667	LOC107087905	ENSCVAP00000021667	ENSCVAP00000031430	Ubiquitin-like domain-containing protein.	Transmembrane phosphatase with tensin homology.	0.586
ENSCVAP00000021667	LOC107094800	ENSCVAP00000021667	ENSCVAP00000030190	Ubiquitin-like domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.586
ENSCVAP00000021667	PTEN	ENSCVAP00000021667	ENSCVAP00000002957	Ubiquitin-like domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.586
ENSCVAP00000021667	atg7	ENSCVAP00000021667	ENSCVAP00000026743	Ubiquitin-like domain-containing protein.	ATG7 autophagy related 7 homolog (S. cerevisiae).	0.747
ENSCVAP00000021667	mkrn1	ENSCVAP00000021667	ENSCVAP00000005840	Ubiquitin-like domain-containing protein.	Makorin, ring finger protein, 1.	0.619
ENSCVAP00000021667	rps27a	ENSCVAP00000021667	ENSCVAP00000003612	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.996
ENSCVAP00000021667	trip12	ENSCVAP00000021667	ENSCVAP00000029886	Ubiquitin-like domain-containing protein.	Thyroid hormone receptor interactor 12.	0.927
ENSCVAP00000021667	uba5	ENSCVAP00000021667	ENSCVAP00000021047	Ubiquitin-like domain-containing protein.	Ubiquitin-like modifier activating enzyme 5.	0.750
LOC107087905	ENSCVAP00000021667	ENSCVAP00000031430	ENSCVAP00000021667	Transmembrane phosphatase with tensin homology.	Ubiquitin-like domain-containing protein.	0.586
LOC107087905	mkrn1	ENSCVAP00000031430	ENSCVAP00000005840	Transmembrane phosphatase with tensin homology.	Makorin, ring finger protein, 1.	0.452
LOC107087905	rps27a	ENSCVAP00000031430	ENSCVAP00000003612	Transmembrane phosphatase with tensin homology.	Ribosomal protein S27a.	0.558
LOC107094800	ENSCVAP00000021667	ENSCVAP00000030190	ENSCVAP00000021667	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin-like domain-containing protein.	0.586
LOC107094800	PTEN	ENSCVAP00000030190	ENSCVAP00000002957	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.901
LOC107094800	mkrn1	ENSCVAP00000030190	ENSCVAP00000005840	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Makorin, ring finger protein, 1.	0.452
LOC107094800	rps27a	ENSCVAP00000030190	ENSCVAP00000003612	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ribosomal protein S27a.	0.558
PTEN	ENSCVAP00000021667	ENSCVAP00000002957	ENSCVAP00000021667	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin-like domain-containing protein.	0.586
PTEN	LOC107094800	ENSCVAP00000002957	ENSCVAP00000030190	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.901
PTEN	mkrn1	ENSCVAP00000002957	ENSCVAP00000005840	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Makorin, ring finger protein, 1.	0.452
PTEN	rps27a	ENSCVAP00000002957	ENSCVAP00000003612	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ribosomal protein S27a.	0.558
atg7	ENSCVAP00000021667	ENSCVAP00000026743	ENSCVAP00000021667	ATG7 autophagy related 7 homolog (S. cerevisiae).	Ubiquitin-like domain-containing protein.	0.747