STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107092244Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family. (215 aa)    
Predicted Functional Partners:
C8A
Complement C8 alpha chain.
  
 0.988
ENSCVAP00000004758
A2M_N_2 domain-containing protein.
   
 0.950
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
   0.855
c9
Complement component 9.
   
 0.801
cdc73
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).
   
 0.759
c8b
Complement component 8, beta polypeptide.
   
 0.757
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.744
cinp
Cyclin-dependent kinase 2 interacting protein.
    
 0.698
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component.
    
 0.698
LOC107092931
Aurora kinase B; Belongs to the protein kinase superfamily.
    
 
 0.591
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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