STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107098322Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)    
Predicted Functional Partners:
tgfb2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.987
LOC107083120
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.982
tgfb3
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.982
LOC107100676
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
0.977
LOC107103699
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.972
smad2
Mothers against decapentaplegic homolog.
   
 0.957
LOC107098778
Mothers against decapentaplegic homolog.
   
 0.957
smad3
Mothers against decapentaplegic homolog.
   
 0.957
SMAD3
Mothers against decapentaplegic homolog.
   
 0.957
LOC107087195
E3 ubiquitin-protein ligase.
    
 0.950
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.