STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
twnkTwinkle mtDNA helicase. (726 aa)    
Predicted Functional Partners:
ssbp1
Single-stranded DNA binding protein 1.
   
  
 0.676
polg
Polymerase (DNA directed), gamma.
   
  
 0.675
polrmt
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.657
tfam
Transcription factor A, mitochondrial.
      
 0.652
polg2
Polymerase (DNA directed), gamma 2, accessory subunit.
      
 0.648
mgme1
Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.
      
 0.602
dna2
DNA replication helicase/nuclease 2.
      
 0.597
rnaseh1
Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
      
 0.589
DGUOK
Deoxyguanosine kinase.
      
 0.589
mpv17
Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.582
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.