STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1120 aa)    
Predicted Functional Partners:
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.971
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
     
 0.960
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.955
LOC107099926
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.955
LOC107083482
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.955
ENSCVAP00000029198
V-akt murine thymoma viral oncogene homolog 3b.
    
 0.955
pik3r6
Uncharacterized protein.
    
 0.953
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
0.937
LOC107102211
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
0.937
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.929
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.