nrbp2 protein (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nrbp2

Nuclear receptor binding protein 2b. (505 aa)

Predicted Functional Partners:

srfbp1

0.574

lonp2

0.571

ENSCVAP00000027620

0.514

exosc4

0.497

LOC107095659

0.450

LOC107095657

0.450

otulin

0.449

tfb1m

0.404

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000027620	nrbp2	ENSCVAP00000027620	ENSCVAP00000007717	Poly [ADP-ribose] polymerase.	Nuclear receptor binding protein 2b.	0.514
LOC107095657	exosc4	ENSCVAP00000022390	ENSCVAP00000023356	Pyrroline-5-carboxylate reductase 3-like.	Exosome component 4.	0.472
LOC107095657	nrbp2	ENSCVAP00000022390	ENSCVAP00000007717	Pyrroline-5-carboxylate reductase 3-like.	Nuclear receptor binding protein 2b.	0.450
LOC107095659	exosc4	ENSCVAP00000003845	ENSCVAP00000023356	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	Exosome component 4.	0.472
LOC107095659	nrbp2	ENSCVAP00000003845	ENSCVAP00000007717	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	Nuclear receptor binding protein 2b.	0.450
exosc4	LOC107095657	ENSCVAP00000023356	ENSCVAP00000022390	Exosome component 4.	Pyrroline-5-carboxylate reductase 3-like.	0.472
exosc4	LOC107095659	ENSCVAP00000023356	ENSCVAP00000003845	Exosome component 4.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.472
exosc4	nrbp2	ENSCVAP00000023356	ENSCVAP00000007717	Exosome component 4.	Nuclear receptor binding protein 2b.	0.497
exosc4	srfbp1	ENSCVAP00000023356	ENSCVAP00000010826	Exosome component 4.	BUD22 domain-containing protein.	0.401
exosc4	tfb1m	ENSCVAP00000023356	ENSCVAP00000007524	Exosome component 4.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.401
lonp2	nrbp2	ENSCVAP00000008704	ENSCVAP00000007717	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	Nuclear receptor binding protein 2b.	0.571
lonp2	srfbp1	ENSCVAP00000008704	ENSCVAP00000010826	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	BUD22 domain-containing protein.	0.583
nrbp2	ENSCVAP00000027620	ENSCVAP00000007717	ENSCVAP00000027620	Nuclear receptor binding protein 2b.	Poly [ADP-ribose] polymerase.	0.514
nrbp2	LOC107095657	ENSCVAP00000007717	ENSCVAP00000022390	Nuclear receptor binding protein 2b.	Pyrroline-5-carboxylate reductase 3-like.	0.450
nrbp2	LOC107095659	ENSCVAP00000007717	ENSCVAP00000003845	Nuclear receptor binding protein 2b.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.450
nrbp2	exosc4	ENSCVAP00000007717	ENSCVAP00000023356	Nuclear receptor binding protein 2b.	Exosome component 4.	0.497
nrbp2	lonp2	ENSCVAP00000007717	ENSCVAP00000008704	Nuclear receptor binding protein 2b.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.571
nrbp2	otulin	ENSCVAP00000007717	ENSCVAP00000025150	Nuclear receptor binding protein 2b.	OTU deubiquitinase with linear linkage specificity a.	0.449
nrbp2	srfbp1	ENSCVAP00000007717	ENSCVAP00000010826	Nuclear receptor binding protein 2b.	BUD22 domain-containing protein.	0.574
nrbp2	tfb1m	ENSCVAP00000007717	ENSCVAP00000007524	Nuclear receptor binding protein 2b.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.404