STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ufm1Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (87 aa)    
Predicted Functional Partners:
uba5
Ubiquitin-like modifier activating enzyme 5.
   
 
 0.979
ufsp2
Ufm1-specific peptidase 2.
    
 
 0.957
Ufsp1
UFM1-specific peptidase 1 (non-functional).
  
 
 
 0.952
Ufc1
Ubiquitin-fold modifier conjugating enzyme 1.
   
 
 0.918
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
 
 0.815
ufl1
UFM1-specific ligase 1.
   
 
 0.758
ddrgk1
Uncharacterized protein.
    
 
 0.742
uba1
Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 
 0.682
LOC107097505
Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 
 0.682
uba6
Ubiquitin like modifier activating enzyme 6.
   
 
 0.682
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.