sp1 protein (Cyprinodon variegatus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

sp1

Sp1 transcription factor. (442 aa)

Predicted Functional Partners:

tp53

0.947

LOC107092878

0.941

ep300

0.941

crebbp

0.852

LOC107083428

0.852

e2f1

0.813

LOC107094552

0.763

LOC107084874

0.763

LOC107081657

0.763

esr1

0.763

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107081657	LOC107083428	ENSCVAP00000020274	ENSCVAP00000019004	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	CREB binding protein a.	0.650
LOC107081657	LOC107084874	ENSCVAP00000020274	ENSCVAP00000008829	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2b.	0.584
LOC107081657	LOC107092878	ENSCVAP00000020274	ENSCVAP00000020689	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	E1A binding protein p300 a.	0.748
LOC107081657	LOC107094552	ENSCVAP00000020274	ENSCVAP00000002387	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2a.	0.586
LOC107081657	crebbp	ENSCVAP00000020274	ENSCVAP00000002467	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	CREB binding protein b.	0.650
LOC107081657	ep300	ENSCVAP00000020274	ENSCVAP00000025385	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	E1A binding protein p300 b.	0.748
LOC107081657	sp1	ENSCVAP00000020274	ENSCVAP00000008098	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Sp1 transcription factor.	0.763
LOC107081657	tp53	ENSCVAP00000020274	ENSCVAP00000022398	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.560
LOC107083428	LOC107081657	ENSCVAP00000019004	ENSCVAP00000020274	CREB binding protein a.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.650
LOC107083428	LOC107084874	ENSCVAP00000019004	ENSCVAP00000008829	CREB binding protein a.	Estrogen receptor 2b.	0.650
LOC107083428	LOC107092878	ENSCVAP00000019004	ENSCVAP00000020689	CREB binding protein a.	E1A binding protein p300 a.	0.937
LOC107083428	LOC107094552	ENSCVAP00000019004	ENSCVAP00000002387	CREB binding protein a.	Estrogen receptor 2a.	0.650
LOC107083428	e2f1	ENSCVAP00000019004	ENSCVAP00000013790	CREB binding protein a.	E2F transcription factor 1.	0.517
LOC107083428	ep300	ENSCVAP00000019004	ENSCVAP00000025385	CREB binding protein a.	E1A binding protein p300 b.	0.937
LOC107083428	esr1	ENSCVAP00000019004	ENSCVAP00000025609	CREB binding protein a.	Estrogen receptor 1.	0.650
LOC107083428	sp1	ENSCVAP00000019004	ENSCVAP00000008098	CREB binding protein a.	Sp1 transcription factor.	0.852
LOC107083428	tp53	ENSCVAP00000019004	ENSCVAP00000022398	CREB binding protein a.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.995
LOC107084874	LOC107081657	ENSCVAP00000008829	ENSCVAP00000020274	Estrogen receptor 2b.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.584
LOC107084874	LOC107083428	ENSCVAP00000008829	ENSCVAP00000019004	Estrogen receptor 2b.	CREB binding protein a.	0.650
LOC107084874	LOC107092878	ENSCVAP00000008829	ENSCVAP00000020689	Estrogen receptor 2b.	E1A binding protein p300 a.	0.748