STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF146Ring finger protein 146. (354 aa)    
Predicted Functional Partners:
ENSCVAP00000010843
Uncharacterized protein.
    
 0.942
LOC107084655
Poly [ADP-ribose] polymerase.
    
 0.906
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.699
parp2
Poly [ADP-ribose] polymerase.
    
 
 0.680
trip12
Thyroid hormone receptor interactor 12.
      
 0.664
LOC107092835
Axin 2 (conductin, axil).
    
 0.646
LOC107097051
Uncharacterized protein.
    
 0.646
AXIN2
Axin 2.
    
 0.646
axin1
Axin 1.
    
 0.646
rps27a
Ribosomal protein S27a.
   
  0.645
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.