STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrispH2_006727Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (260 aa)    
Predicted Functional Partners:
TrispH2_008058
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.980
TrispH2_009678
RING-box protein 1A.
    
 0.979
TrispH2_004323
UBX domain-containing protein 7.
     
 0.976
TrispH2_006715
Cullin-3-B; Belongs to the cullin family.
   
 0.971
TrispH2_002770
Cullin-1; Belongs to the cullin family.
   
 0.968
TrispH2_001516
NEDD8.
    
 0.948
TrispH2_006614
CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family.
   
 0.929
TrispH2_004324
Cullin-4A; Belongs to the cullin family.
    
 0.909
TrispH2_008593
Cullin-2; Belongs to the cullin family.
   
 0.882
TrispH2_001893
Cullin-5; Belongs to the cullin family.
   
 0.879
Your Current Organism:
Trichoplax sp. H2
NCBI taxonomy Id: 287889
Other names: T. sp. H2
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