STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrispH2_007379Cyclin-dependent kinase 2-interacting protein. (222 aa)    
Predicted Functional Partners:
TrispH2_000237
RNA polymerase-associated protein LEO1.
   
 0.999
TrispH2_008601
RNA polymerase II-associated factor 1-like protein.
   
 0.916
TrispH2_003102
Parafibromin.
   
 0.915
TrispH2_005908
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.908
TrispH2_007686
RNA polymerase-associated protein RTF1-like protein.
   
 0.906
TrispH2_000175
FACT complex subunit SPT16.
   
 0.900
TrispH2_003833
DNA-directed RNA polymerase II subunit RPB3.
    
 0.859
TrispH2_000504
Histone H2B; Belongs to the histone H2B family.
    
 0.851
TrispH2_001998
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.795
TrispH2_008086
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 0.791
Your Current Organism:
Trichoplax sp. H2
NCBI taxonomy Id: 287889
Other names: T. sp. H2
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