STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrispH2_002043DNA repair protein RAD51-like protein 4. (338 aa)    
Predicted Functional Partners:
TrispH2_011604
Fanconi anemia group M protein.
   
 0.998
TrispH2_004380
Werner syndrome ATP-dependent helicase-like protein.
  
 0.998
TrispH2_001687
DNA repair protein XRCC2.
   
 0.983
TrispH2_006847
Breast cancer type 2 susceptibility protein.
   
 0.968
TrispH2_003011
DNA repair protein RAD51-like protein 3.
   
0.963
TrispH2_005620
DNA repair protein XRCC3.
    
0.957
TrispH2_010035
DNA repair protein RAD51-like protein 2.
   
0.953
TrispH2_008087
DNA repair protein RAD52-like protein.
    
 0.945
TrispH2_002012
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
  
 0.927
TrispH2_005582
Crossover junction endonuclease MUS81.
   
 0.909
Your Current Organism:
Trichoplax sp. H2
NCBI taxonomy Id: 287889
Other names: T. sp. H2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.