STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0115_0081DNA polymerase. (1612 aa)    
Predicted Functional Partners:
Esi_0090_0069
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.999
Esi_0086_0039
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.998
Esi_0435_0009
WD_REPEATS_REGION domain-containing protein.
   
 
 0.997
Esi_0269_0016
Similar to DNA primase large subunit, partial.
   
 0.996
Esi_0192_0018
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
 0.996
Esi_0002_0190
DNA helicase; Belongs to the MCM family.
   
 0.990
Esi_0021_0097
Uncharacterized protein.
   
 0.987
Esi_0029_0091
DNA helicase; Belongs to the MCM family.
   
 0.984
Esi_0063_0095
DNA helicase; Belongs to the MCM family.
   
 0.981
Esi_0002_0068
Similar to CTF18, chromosome transmission fidelity factor 18 homolog isoform 3.
   
 0.980
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.