STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0136_0078Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (KAP alpha). (1148 aa)    
Predicted Functional Partners:
Esi_0013_0190
Importin N-terminal domain-containing protein.
   
 0.883
Esi_0141_0047
Importin N-terminal domain-containing protein.
   
 0.812
Esi_0141_0049
CAS_CSE1 domain-containing protein.
   
 0.812
Esi_0155_0015
Uncharacterized protein.
   
 
 0.709
Esi_0003_0066
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
   0.705
Esi_0206_0003
Nuclear cap-binding protein subunit 2.
    
 
 0.699
Esi_0073_0086
RanBD1 domain-containing protein.
   
 
 0.691
RAN
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.674
Esi_0029_0059
Uncharacterized protein.
    
 
 0.612
Esi_0103_0028
Uncharacterized protein.
    
 
 0.612
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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