STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0144_0006Similar to Iron-containing Alcohol Dehydrogenase. (428 aa)    
Predicted Functional Partners:
Esi_0162_0015
PepX_C domain-containing protein.
   
 0.926
FDH1
Formaldehyde dehydrogenase.
   
 0.926
Esi_0168_0057
D-isomer specific 2-hydroxyacid dehydrogenase.
  
 
 0.784
Esi_0308_0033
Aldehyde dehydrogenase.
  
 0.755
Esi_0451_0004
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.755
Esi_0010_0069
Aldehyde Dehydrogenase.
  
 0.755
NUOI
NUOI homolog, NADH dehydrogenase (Ubiquinone) subunit.
    
 0.753
Esi_0154_0047
Hydroxyacyl-Coenzyme A dehydrogenase.
  
 
 0.741
SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.740
Esi_0000_0452
NADPH:adrenodoxin oxidoreductase, mitochondrial.
    
 0.734
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.