STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0018_0114Uncharacterized protein. (731 aa)    
Predicted Functional Partners:
Esi_0000_0340
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
    
 0.922
Esi_0069_0033
Pterin-binding domain-containing protein.
 
 
 0.886
Esi_0219_0001
Folate gamma-glutamyl hydrolase.
     
 0.747
Esi_0339_0028
GTP cyclohydrolase I.
  
  
 0.671
Esi_0027_0012
Flavoprotein family enzyme.
    
 0.670
COX19
COX19 homolog, cytochrome c oxidase assembly protein.
    
 0.670
Esi_0053_0080
Uncharacterized protein.
    
 0.641
Esi_0169_0021
Nudix hydrolase domain-containing protein.
    
 0.629
Esi_0018_0066
MutT-like protein.
    
 0.629
Esi_0111_0024
ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
    
 0.629
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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