STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALARSAlanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (992 aa)    
Predicted Functional Partners:
APC6-cdc16
Putative subunit of the Anaphase Promoting Complex.
   
 0.930
APC4
Putative subunit of the Promoting Anaphase Complex.
   
 0.927
APC5
Putative subunit of the Anaphase Promoting Complex.
   
 0.926
APC11
Putative subunit of the Anaphase Promoting Complex.
    
 0.924
APC10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.924
APC1
Putative subunit of the Anaphase Promoting Complex.
    
 0.924
APC7
Putative subunit of the Anaphase Promoting Complex.
   
 0.909
Esi_0022_0115
HORMA domain protein.
    
 0.847
Esi_0080_0002
Uncharacterized protein.
    
 0.841
APC2-Cullin
Belongs to the cullin family.
    
 0.841
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.