STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0002_00122-hydroxy-3-oxopropionate reductase. (293 aa)    
Predicted Functional Partners:
Esi_0180_0009
Putative 3-ketoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.758
Esi_0046_0105
Uncharacterized protein.
    
 0.750
Esi_0196_0052
Uncharacterized protein.
    
  0.740
Esi_0013_0022
TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
  0.739
Esi_0384_0016
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.739
Esi_0107_0021
RPOLD domain-containing protein.
    
  0.725
Esi_0032_0021
Methylmalonate Semialdehyde Dehydrogenase.
   
 0.723
MSDH
Methylmalonate Semialdehyde Dehydrogenase.
   
 0.723
Esi_0552_0011
RNA polymerase II core subunit.
    
  0.722
Esi_0000_0121
Uncharacterized protein.
    
 0.719
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.