STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0223_0029Uncharacterized protein. (236 aa)    
Predicted Functional Partners:
GSKa
Glycogen synthase kinase-3 beta (GSK-3 beta); Belongs to the protein kinase superfamily.
    
 0.919
CK-2
Casein kinase (Serine/threonine/tyrosine protein kinase) casein kinase I.
   
 0.836
Esi_0026_0117
RuvB-like helicase; Belongs to the RuvB family.
   
 0.822
Esi_0059_0066
Uncharacterized protein.
    
 0.801
WD40
Possible ribosome assembly protein 4.
    
 0.791
Esi_0015_0085
WD-40 repeat protein.
    
 0.791
Esi_0022_0161
RNA pol II accessory factor, Cdc73 family protein.
    
 0.762
Esi_0009_0210
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.760
Esi_0224_0050
Uncharacterized protein.
    
 
 0.737
Esi_0002_0184
Hypothetical leucine rich repeat protein.
  
 0.733
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.