STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0029_0071Similar to histidine triad protein 4. (215 aa)    
Predicted Functional Partners:
Esi_0115_0055
Cytochrome b5 heme-binding domain-containing protein.
  
  0.818
Nia
NAD(P)H-Nitrate reductase.
  
  0.818
Esi_0042_0003
SprT-like domain-containing protein.
    
 0.721
Esi_0029_0017
Uncharacterized protein.
   
 0.699
Esi_0042_0019
Transcription initiation factor TFIID.
   
 0.699
Esi_0000_0340
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
  0.623
Esi_0238_0005
Nudix hydrolase domain-containing protein.
  
 0.621
Esi_0031_0124
Nudix hydrolase domain-containing protein.
  
 0.621
Esi_0010_0022
Nudix hydrolase domain-containing protein.
   
 0.619
Esi_0012_0174
Adenylate kinase family protein.
   
 0.619
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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