Esi_0029_0071 protein (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Esi_0029_0071

Similar to histidine triad protein 4. (215 aa)

Predicted Functional Partners:

Esi_0115_0055

0.818

Nia

0.818

Esi_0042_0003

0.721

Esi_0029_0017

0.699

Esi_0042_0019

0.699

Esi_0000_0340

0.623

Esi_0238_0005

0.621

Esi_0031_0124

0.621

Esi_0010_0022

0.619

Esi_0012_0174

0.619

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0000_0340	Esi_0029_0071	D8LBA4	D7FVB6	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Similar to histidine triad protein 4.	0.623
Esi_0000_0340	Esi_0115_0055	D8LBA4	D7FHZ6	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Cytochrome b5 heme-binding domain-containing protein.	0.528
Esi_0000_0340	Nia	D8LBA4	D8LQI2	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	NAD(P)H-Nitrate reductase.	0.528
Esi_0010_0022	Esi_0029_0071	D8LBW5	D7FVB6	Nudix hydrolase domain-containing protein.	Similar to histidine triad protein 4.	0.619
Esi_0012_0174	Esi_0029_0071	D8LDL6	D7FVB6	Adenylate kinase family protein.	Similar to histidine triad protein 4.	0.619
Esi_0029_0017	Esi_0029_0071	D7FV81	D7FVB6	Uncharacterized protein.	Similar to histidine triad protein 4.	0.699
Esi_0029_0017	Esi_0042_0003	D7FV81	D7G0U3	Uncharacterized protein.	SprT-like domain-containing protein.	0.815
Esi_0029_0071	Esi_0000_0340	D7FVB6	D8LBA4	Similar to histidine triad protein 4.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.623
Esi_0029_0071	Esi_0010_0022	D7FVB6	D8LBW5	Similar to histidine triad protein 4.	Nudix hydrolase domain-containing protein.	0.619
Esi_0029_0071	Esi_0012_0174	D7FVB6	D8LDL6	Similar to histidine triad protein 4.	Adenylate kinase family protein.	0.619
Esi_0029_0071	Esi_0029_0017	D7FVB6	D7FV81	Similar to histidine triad protein 4.	Uncharacterized protein.	0.699
Esi_0029_0071	Esi_0031_0124	D7FVB6	D8LKY4	Similar to histidine triad protein 4.	Nudix hydrolase domain-containing protein.	0.621
Esi_0029_0071	Esi_0042_0003	D7FVB6	D7G0U3	Similar to histidine triad protein 4.	SprT-like domain-containing protein.	0.721
Esi_0029_0071	Esi_0042_0019	D7FVB6	D7G0V1	Similar to histidine triad protein 4.	Transcription initiation factor TFIID.	0.699
Esi_0029_0071	Esi_0115_0055	D7FVB6	D7FHZ6	Similar to histidine triad protein 4.	Cytochrome b5 heme-binding domain-containing protein.	0.818
Esi_0029_0071	Esi_0238_0005	D7FVB6	D7FSP6	Similar to histidine triad protein 4.	Nudix hydrolase domain-containing protein.	0.621
Esi_0029_0071	Nia	D7FVB6	D8LQI2	Similar to histidine triad protein 4.	NAD(P)H-Nitrate reductase.	0.818
Esi_0031_0124	Esi_0029_0071	D8LKY4	D7FVB6	Nudix hydrolase domain-containing protein.	Similar to histidine triad protein 4.	0.621
Esi_0042_0003	Esi_0029_0017	D7G0U3	D7FV81	SprT-like domain-containing protein.	Uncharacterized protein.	0.815
Esi_0042_0003	Esi_0029_0071	D7G0U3	D7FVB6	SprT-like domain-containing protein.	Similar to histidine triad protein 4.	0.721