STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APC4Putative subunit of the Promoting Anaphase Complex. (912 aa)    
Predicted Functional Partners:
APC5
Putative subunit of the Anaphase Promoting Complex.
   
 0.999
APC11
Putative subunit of the Anaphase Promoting Complex.
    
 0.999
APC10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.999
APC1
Putative subunit of the Anaphase Promoting Complex.
   
 0.999
APC6-cdc16
Putative subunit of the Anaphase Promoting Complex.
   
 0.999
Esi_0098_0002
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.998
Esi_0117_0003
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.997
APC7
Putative subunit of the Anaphase Promoting Complex.
   
 0.995
Esi_0022_0115
HORMA domain protein.
    
 0.993
Esi_0076_0010
WD-40 repeat family protein / mitotic checkpoint protein, putative.
    
 0.991
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.