STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0393_0020Topo_C_assoc domain-containing protein. (122 aa)    
Predicted Functional Partners:
Esi_0489_0018
SWIB domain-containing protein.
    
   0.863
TOP2
DNA topoisomerase II.
   
 
 0.813
Esi_0056_0068
DNA gyrase subunit A.
   
 
 0.813
TOP4B
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner.
   
 
 0.813
Esi_0029_0113
Small ubiquitin-like modifier.
    
 0.806
Esi_0036_0023
Small ubiquitin-like modifier.
    
 0.806
Esi_0216_0042
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.796
Esi_0054_0059
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.796
Esi_0122_0003
Uncharacterized protein.
    
 
 0.789
TYDP
Tyrosyl-DNA phosphodiesterase.
    
 
 0.789
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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