STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0403_0011Uncharacterized protein. (340 aa)    
Predicted Functional Partners:
Esi_0047_0052
TAFII55_N domain-containing protein.
    
 
 0.657
Esi_0324_0025
SANT_DAMP1_like domain-containing protein.
    
 
 0.508
Esi_0124_0012
Bromo domain-containing protein.
    
 
0.480
Esi_0306_0031
Histone H2A; Belongs to the histone H2A family.
    
 
 0.476
Esi_0026_0117
RuvB-like helicase; Belongs to the RuvB family.
    
 
 0.468
Esi_0057_0057
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.464
Esi_0442_0011
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.464
Esi_0015_0113
BCNT-C domain-containing protein.
    
 
 0.464
Esi_0254_0027
RuvB-like helicase; Belongs to the RuvB family.
    
 
 0.464
Esi_0081_0073
Transmembrane protein, putative.
    
 
 0.464
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.