TOP2 protein (Ectocarpus siliculosus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

TOP2

DNA topoisomerase II. (1809 aa)

Predicted Functional Partners:

Esi_0393_0013

0.813

Esi_0393_0020

0.813

Esi_0029_0113

0.795

Esi_0036_0023

0.795

Esi_0114_0045

0.760

Esi_0098_0002

0.751

Esi_0060_0047

0.741

Esi_0101_0095

0.730

Esi_0002_0285

0.730

Esi_0000_0340

0.725

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0000_0340	Esi_0002_0285	D8LBA4	D7FQC9	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	SMC_N domain-containing protein.	0.795
Esi_0000_0340	Esi_0029_0113	D8LBA4	D7FVD5	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Small ubiquitin-like modifier.	0.520
Esi_0000_0340	Esi_0036_0023	D8LBA4	D8LLA0	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Small ubiquitin-like modifier.	0.520
Esi_0000_0340	Esi_0098_0002	D8LBA4	D7G9D3	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.641
Esi_0000_0340	Esi_0101_0095	D8LBA4	D7FGT8	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	SMC2 (STRUCTURAL MAINTENANCE OF CHROMOSOMES 2).	0.795
Esi_0000_0340	Esi_0114_0045	D8LBA4	D8LD70	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Uncharacterized protein.	0.524
Esi_0000_0340	Esi_0393_0013	D8LBA4	D7G042	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	TOPEUc domain-containing protein.	0.412
Esi_0000_0340	Esi_0393_0020	D8LBA4	D7G047	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	Topo_C_assoc domain-containing protein.	0.412
Esi_0000_0340	TOP2	D8LBA4	D7G0Y6	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	DNA topoisomerase II.	0.725
Esi_0002_0285	Esi_0000_0340	D7FQC9	D8LBA4	SMC_N domain-containing protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.795
Esi_0002_0285	Esi_0029_0113	D7FQC9	D7FVD5	SMC_N domain-containing protein.	Small ubiquitin-like modifier.	0.643
Esi_0002_0285	Esi_0036_0023	D7FQC9	D8LLA0	SMC_N domain-containing protein.	Small ubiquitin-like modifier.	0.643
Esi_0002_0285	Esi_0098_0002	D7FQC9	D7G9D3	SMC_N domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.640
Esi_0002_0285	Esi_0114_0045	D7FQC9	D8LD70	SMC_N domain-containing protein.	Uncharacterized protein.	0.995
Esi_0002_0285	TOP2	D7FQC9	D7G0Y6	SMC_N domain-containing protein.	DNA topoisomerase II.	0.730
Esi_0029_0113	Esi_0000_0340	D7FVD5	D8LBA4	Small ubiquitin-like modifier.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.520
Esi_0029_0113	Esi_0002_0285	D7FVD5	D7FQC9	Small ubiquitin-like modifier.	SMC_N domain-containing protein.	0.643
Esi_0029_0113	Esi_0060_0047	D7FVD5	D8LQR5	Small ubiquitin-like modifier.	Similar to retinoic acid induced 17, partial.	0.979
Esi_0029_0113	Esi_0098_0002	D7FVD5	D7G9D3	Small ubiquitin-like modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.723
Esi_0029_0113	Esi_0101_0095	D7FVD5	D7FGT8	Small ubiquitin-like modifier.	SMC2 (STRUCTURAL MAINTENANCE OF CHROMOSOMES 2).	0.643