STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0506_0006E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (998 aa)    
Predicted Functional Partners:
Esi_0108_0001
Uncharacterized protein.
   
 0.970
Esi_0108_0002
Uncharacterized protein.
   
 0.970
Esi_0357_0001
Uncharacterized protein.
   
 0.970
Esi_0560_0001
HECT domain-containing protein.
   
 0.970
Esi_0435_0012
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.870
Esi_0435_0014
Uncharacterized protein.
    
 
 0.870
Esi_0302_0019
Similar to ubiquitin.
   
 0.664
Esi_0010_0201
Uncharacterized protein.
   
 0.664
Esi_0023_0071
Similar polyubiquitin.
   
 0.664
Esi_0056_0096
Uncharacterized protein.
   
 0.620
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.