STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GDH2Glutamate dehydrogenase 2 (NADP-dependent); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (534 aa)    
Predicted Functional Partners:
P5CS
Delta-1-pyrroline-5-carboxylate synthase.
    
 0.912
Esi_0006_0214
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.861
AAT
Aspartate aminotransferase.
   
 0.847
Esi_0000_0452
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 0.846
GLURS
Glutamyl-tRNA Synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.839
Esi_0292_0040
Uncharacterized protein.
  
 0.833
Esi_1167_0001
Ferredoxin-dependent glutamate synthase.
  
 0.826
GOGAT
Glutamate synthase (NADH/NADPH-dependent).
  
 0.826
Esi_0349_0025
Glutamate synthase, N-terminal.
  
 0.826
Esi_0000_0281
Glutamate synthase (Ferredoxin-dependent).
  
 0.826
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.