STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0054_0105Acyl-CoA thioesterase, putative. (555 aa)    
Predicted Functional Partners:
Esi_0154_0047
Hydroxyacyl-Coenzyme A dehydrogenase.
  
 
 0.802
ACAT1
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.767
Esi_0040_0041
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.753
Esi_0089_0087
Acetoacetate--CoA ligase.
    
 0.743
Esi_0014_0168
Acetyl-coenzyme A synthetase.
    
 0.743
SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
  0.715
Esi_0311_0006
Uncharacterized protein.
    
  0.699
ACAT3
Acetyl-CoA acetyltransferase subunit, putative mitochondrial presursor Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.688
ACAA
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.687
ACAT2
Acetyl-CoA acetyltransferase, putative mitochondrial presursor; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.687
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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