STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0014_0225C3HC-type domain-containing protein. (488 aa)    
Predicted Functional Partners:
Esi_0046_0039
Uncharacterized protein; Belongs to the SKP1 family.
    
  0.743
Esi_0049_0101
Uncharacterized protein; Belongs to the SKP1 family.
    
  0.743
Esi_0079_0055
RING-type domain-containing protein.
    
 0.541
Esi_0079_0058
RING-type domain-containing protein.
    
 0.541
Esi_0033_0150
Uncharacterized protein.
   
    0.483
Esi_0181_0013
Uncharacterized protein.
   
    0.483
Esi_0030_0090
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
   
    0.483
Esi_0081_0020
ATP-grasp domain-containing protein.
   
    0.481
FPPS
Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.464
Esi_0135_0030
Cullin domain-containing protein; Belongs to the cullin family.
    
  0.449
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.