Esi_0158_0014 protein (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Esi_0158_0014

Helicase ATP-binding domain-containing protein. (572 aa)

Predicted Functional Partners:

Esi_0158_0020

0.944

Esi_0217_0013

0.917

Esi_0151_0057

0.916

Esi_0115_0040

0.915

Esi_0000_0653

0.915

Esi_0103_0026

0.905

cyc-4

0.899

MLH1

0.889

Esi_0046_0105

0.865

Esi_0196_0052

0.864

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0000_0653	Esi_0046_0105	D8LBU7	D7G1Y9	RING-type domain-containing protein.	Uncharacterized protein.	0.984
Esi_0000_0653	Esi_0103_0026	D8LBU7	D8LCF1	RING-type domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.993
Esi_0000_0653	Esi_0115_0040	D8LBU7	D7FHY7	RING-type domain-containing protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.994
Esi_0000_0653	Esi_0151_0057	D8LBU7	D8LFT0	RING-type domain-containing protein.	TFIIH subunit (Partial).	0.994
Esi_0000_0653	Esi_0158_0014	D8LBU7	D8LG74	RING-type domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.915
Esi_0000_0653	Esi_0158_0020	D8LBU7	D8LG75	RING-type domain-containing protein.	HELICc2 domain-containing protein.	0.915
Esi_0000_0653	Esi_0196_0052	D8LBU7	D8LHK5	RING-type domain-containing protein.	Uncharacterized protein.	0.985
Esi_0000_0653	Esi_0217_0013	D8LBU7	D7FRP7	RING-type domain-containing protein.	General transcription factor IIH subunit.	0.996
Esi_0000_0653	cyc-4	D8LBU7	D8LRJ6	RING-type domain-containing protein.	Cyclin H; Belongs to the cyclin family.	0.999
Esi_0046_0105	Esi_0000_0653	D7G1Y9	D8LBU7	Uncharacterized protein.	RING-type domain-containing protein.	0.984
Esi_0046_0105	Esi_0103_0026	D7G1Y9	D8LCF1	Uncharacterized protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.993
Esi_0046_0105	Esi_0115_0040	D7G1Y9	D7FHY7	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.984
Esi_0046_0105	Esi_0151_0057	D7G1Y9	D8LFT0	Uncharacterized protein.	TFIIH subunit (Partial).	0.983
Esi_0046_0105	Esi_0158_0014	D7G1Y9	D8LG74	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.865
Esi_0046_0105	Esi_0158_0020	D7G1Y9	D8LG75	Uncharacterized protein.	HELICc2 domain-containing protein.	0.865
Esi_0046_0105	Esi_0196_0052	D7G1Y9	D8LHK5	Uncharacterized protein.	Uncharacterized protein.	0.999
Esi_0046_0105	Esi_0217_0013	D7G1Y9	D7FRP7	Uncharacterized protein.	General transcription factor IIH subunit.	0.984
Esi_0046_0105	cyc-4	D7G1Y9	D8LRJ6	Uncharacterized protein.	Cyclin H; Belongs to the cyclin family.	0.970
Esi_0103_0026	Esi_0000_0653	D8LCF1	D8LBU7	HTH TFE/IIEalpha-type domain-containing protein.	RING-type domain-containing protein.	0.993
Esi_0103_0026	Esi_0046_0105	D8LCF1	D7G1Y9	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.993