STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSDH-2Homoserine dehydrogenase. (434 aa)    
Predicted Functional Partners:
HSK
Homoserine kinase.
  
 0.957
TS
Threonine synthase.
  
 0.955
ilvH
Acetolactate synthase small subunit.
  
 
 0.937
Esi_0036_0051
Tryptophan synthase (Alpha / beta chains).
  
 
 0.904
Esi_0060_0108
Tryptophan synthase (Alpha / beta chains).
  
 
 0.904
Esi_0002_0158
Aspartate-semialdehyde dehydrogenase.
  
 0.897
AK1
Aspartokinase; Belongs to the aspartokinase family.
  
 0.894
Esi_0009_0096
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.
  
 
 0.820
Esi_0011_0179
PALP domain-containing protein.
  
 
 0.773
TAL2
Threonine dehydratase.
  
 
 0.773
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.