STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrxRThioredoxin reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (773 aa)    
Predicted Functional Partners:
Esi_0121_0055
Thioredoxin reductase.
  
 0.940
Esi_0358_0029
Branched chain alpha-keto acid dehydrogenase E1 beta subunit.
  
 0.864
PDH-3
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.864
OGDC
Oxoglutarate dehydrogenase, N-terminal part.
  
 0.829
OGDC-2
Oxoglutarate dehydrogenase E1 subunit, C-terminal.
  
 0.829
Esi_0006_0214
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.801
Esi_0102_0069
Lipoyl-binding domain-containing protein.
  
 0.793
Esi_0163_0048
Dihydrolipoamide S-acetyltransferase.
  
 0.793
PDH
Pyruvate dehydrogenase E1 component subunit beta.
  
 0.793
Esi_0305_0003
Dihydrolipoamide succinyltransferase.
  
 0.793
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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