STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0254_0018Domain repeat protein. (579 aa)    
Predicted Functional Partners:
RAN
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.705
Esi_0073_0086
RanBD1 domain-containing protein.
    
 0.696
Esi_0023_0105
Uncharacterized protein.
  
 
  0.680
RAC
RAC, RHO family GTPase.
    
 0.574
Esi_0037_0094
Histone H2B; Belongs to the histone H2B family.
    
 0.567
psaF
Photosystem I subunit III.
   
 
 0.565
psaC
Photosystem I iron-sulfur center; Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized accepto [...]
    
 
 0.559
psaE
Photosystem I reaction center subunit IV.
   
 
 0.554
psaD
Photosystem I reaction center subunit II.
   
 
 0.554
Esi_0171_0015
Putative serine-threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.552
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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