STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCAIRNCAIR mutase (PurE)-related proteins. (332 aa)    
Predicted Functional Partners:
Esi_0081_0020
ATP-grasp domain-containing protein.
  
 0.997
Adsl
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.958
Esi_0031_0020
Probable bifunctional purine synthesis protein.
  
 0.914
Esi_0019_0004
ACT domain-containing protein.
  
 0.905
Esi_0334_0008
Uncharacterized protein.
  
 0.903
Esi_0125_0011
Amidophosphoribosyltransferase.
  
 0.880
Esi_0024_0138
Amidophosphoribosyltransferase.
  
 0.880
Esi_0220_0048
Glutamine amidotransferase type-1 domain-containing protein.
  
 0.879
Esi_0220_0051
Uncharacterized protein.
  
 0.879
Esi_0308_0007
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 0.844
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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