STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Esi_0005_0203DDHD domain-containing protein. (682 aa)    
Predicted Functional Partners:
SEC31
Vesicle coat complex COPII, subunit SEC31.
    
 0.817
Esi_0159_0033
WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.
    
 0.767
SEC23
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 0.717
Esi_0174_0020
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 0.717
SNR2
Soluble NSF Attachment Protein (SNAP) Receptor (SNARE); Belongs to the synaptobrevin family.
     
 0.705
Esi_0254_0024
Protein transport protein sec16; Belongs to the SEC16 family.
     
 0.661
SNR20
Soluble NSF Attachment Protein (SNAP) Receptor (SNARE).
   
 
  0.660
Sar1B
Sar1B, Ras superfamily GTPase; Belongs to the small GTPase superfamily. Arf family.
     
 0.599
Sar1A
Sar1A, Ras superfamily GTPase; Belongs to the small GTPase superfamily. SAR1 family.
     
 0.599
Esi_0003_0210
Sec23/sec24 transport protein-related.
   
 
 0.575
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.