STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPKK-2Mitogen-activated protein kinase kinase (MAP2K); Belongs to the protein kinase superfamily. (316 aa)    
Predicted Functional Partners:
Esi_0121_0057
ATP binding protein.
  
0.912
Esi_0195_0008
CSD domain-containing protein.
    
 0.795
Esi_0198_0013
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
 
 0.787
Esi_0131_0026
SH3 domain-containing protein.
    
 0.751
MAPK-6
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
 
0.750
MAPK-4
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
 
0.735
Esi_0141_0059
Uncharacterized protein.
  
 
 0.717
Esi_0271_0004
Mitogen-activated protein kinase.
  
 
0.717
Esi_0271_0006
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
 
0.715
Esi_0403_0008
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
 
0.712
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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