STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupL-2Uptake hydrogenase large subunit precursor; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (596 aa)    
Predicted Functional Partners:
hupS
Uptake hydrogenase small subunit precursor; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein.
 
 0.999
hupU-2
Uptake hydrogenase accessory; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic.
 
 0.998
hupC
Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein.
 
 
 0.996
hupU
Uptake hydrogenase accessory protein hupU; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic.
 
 0.995
hupD
Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
 
 
 0.971
hupV
Uptake hydrogenase accessory; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic.
 
  
 
0.954
hupF
Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
 
 
 0.942
hupH
Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
 
  
 0.929
hupG
Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the HupG/HyaE family.
 
 
 0.924
hupL
Uptake hydrogenase large subunit; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic; PUBMED: 15528652.
  
  
 
0.918
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.